New DHHS Perinatal HIV Guidelines

  • For couples in which one partner has HIV and the other does not, sexual intercourse without a condom limited to 2–3 days before and the day of ovulation is a way to conceive that carries "effectively no risk" of HIV transmission as long as the person with HIV is on ART and has achieved sustained virologic suppression.
  • Regardless of CD4 cell count, ART should be started as early as possible during pregnancy or, even better, before conception.
  • Dolutegravir is not recommended during the first trimester or in women who are trying to conceive.
  • Dolutegravir is a preferred medication in the second and third trimesters.
  • Preferred regimens: TDF/ABC + 3TC/FTC + RAL/DTG/DRV-rtv/ATV-rtv